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目的通过与两种常用的结核病快速诊断技术的比较,评价CBA检测方法在结核病诊断中的价值,为临床治疗提供参考依据。方法选取医院2015年3月-12月收治的住院患者191例,运用CBA技术、T-SPOT和结核分枝杆菌抗体检测对所有入组对象进行双盲检测,并对检测结果统计分析。结果 CBA检测的敏感性为86.82%,比T-SPOT 75.19%和结核分枝杆菌抗体检测38.76%均高,差异有统计学意义(P<0.05);CBA检测结果的特异性为91.94%,比T-SPOT 82.26%和结核分枝杆菌抗体检测的83.87%均高。结论 CBA技术的检测结果能有效的区分活动性结核病和其他肺部疾病,有利于控制结核病疫情的流行,为实现最终消灭结核病的长远目标提供了可靠的技术方法。
Objective To evaluate the value of CBA detection in the diagnosis of tuberculosis by comparing with two commonly used rapid diagnostic techniques for tuberculosis and provide a reference for clinical treatment. Methods Totally 191 hospitalized patients were selected from March 2015 to December 2015 in our hospital. All patients were double-blindly detected by CBA, T-SPOT and Mycobacterium tuberculosis antibody test, and the results were statistically analyzed. Results The sensitivity of CBA was 86.82%, which was higher than that of T-SPOT 75.19% and M. tuberculosis antibody 38.76% (P <0.05). The specificity of CBA was 91.94% T-SPOT 82.26% and M. tuberculosis antibody test 83.87% were high. Conclusions The results of CBA techniques can effectively distinguish active tuberculosis and other pulmonary diseases and control the epidemic of tuberculosis and provide a reliable technical method for achieving the long-term goal of eventually eliminating tuberculosis.