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在细胞免疫反应中,致敏的淋巴细胞与其相应的抗原相互作用时分泌出大量的具有不同生物活性的可溶性因子,即淋巴因子。这些淋巴因子能诱导淋巴细胞及吞噬细胞在炎症局部集聚,发挥抗感染或抗肿瘤等作用。转移因子就是其中的一种,它可将免疫反应活性转移给正常未致敏的细胞,使之成为致敏的淋巴细胞,从而扩大细胞免疫反应。目前多由白细胞、淋巴组织的溶解物获得转移因子,其分子量约为3500～5000,无抗原性,可透析、可超滤,低温稳定,但不耐高温,50℃30分钟可失活,在一定的实验条件下,其生物活性不为DNA酶、RNA酶及胰蛋白酶破坏,具有特异性传递细
In the cellular immune response, sensitized lymphocytes, when interacting with their corresponding antigens, secrete large quantities of soluble factors with different biological activities, namely lymphokines. These lymphokines can induce lymphocytes and phagocytes in local inflammation accumulation, play anti-infection or anti-tumor effect. Transfer factor is one of them, it can transfer the immune activity to normal non-sensitized cells, making it sensitized lymphocytes, thereby expanding the cellular immune response. At present, many leukocytes and lymphatic tissue lysates obtain transfer factor, the molecular weight of about 3500-5000, no antigenicity, dialysis, ultrafiltration, low temperature stability, but not high temperature, 50 ℃ 30 minutes inactivation, at Under certain experimental conditions, its biological activity is not damaged by DNase, RNase and trypsin, with specific transmission of fine