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目的了解河南省2016年健康人群麻疹、风疹、流行性腮腺炎(流腮)抗体水平。方法采用系统抽样方法选择河南省3个县(区)8个年龄组共449名健康人采集血标本,用酶联免疫吸附试验(ELISA)测定血清中麻疹、风疹、流腮Ig G抗体。结果在449名监测对象中,麻疹、风疹、流腮抗体阳性率分别为93.99%、88.42%、87.08%,抗体几何平均浓度(GMC)分别为1 180.57m IU/ml、78.57IU/ml、555.69IU/ml。麻疹和风疹抗体阳性率在各年龄组之间无显著性差异、各地区之间有显著性差异;流腮抗体阳性率在各年龄组之间有显著性差异,在地区之间无显著性差异。麻疹和流腮GMC在各年龄组和地区之间均有显著性差异,风疹GMC在各地区间有显著性差异,在年龄组之间无显著性差异。结论河南省健康人群麻疹、风疹、流腮抗体水平整体较高,需加强弱势区域和重点年龄组含麻疹、风疹、流腮成分疫苗的接种工作。
Objective To understand the levels of measles, rubella and mumps antibody in healthy population in Henan Province in 2016. Methods Blood samples were collected from 449 healthy people in 8 age groups of 3 counties (districts) in Henan Province by systematic sampling method. The Ig G antibodies in measles, rubella and mumps in serum were detected by enzyme - linked immunosorbent assay (ELISA). Results The positive rates of measles, rubella and mumps in 449 subjects were 93.99%, 88.42% and 87.08% respectively. The antibody mean geometric mean concentrations (GMCs) were 1 180.57m IU / ml, 78.57IU / ml and 555.69 IU / ml. Measles and rubella antibody positive rates in all age groups no significant difference between the regions were significantly different; mumps antibody positive rate in all age groups were significantly different, no significant difference between regions . Measles and gills GMC in all age groups and regions were significantly different, rubella GMC significant differences between regions, no significant differences between age groups. Conclusion The levels of measles, rubella and mumps in healthy population in Henan Province are generally high. Vaccination with measles, rubella and mumps vaccines in vulnerable and key age groups should be strengthened.