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目的 :研究高原青年移居者血液凝血纤溶系统的状态。方法 :检测 38例青年移居者血浆组织型纤溶酶原激活物 (t -PA)、纤溶酶原激活物抑制剂 (PAI)和纤维蛋白原 (Fbg)含量 ,并与 36例健康藏族世居青年进行比较。以平原健康青年作为对照。结果 :移居者较藏族世居组及对照组t -PA活性降低 (P <0 .0 5 ) ,PAI活性增高 (P <0 .0 5 ) ,各组之间Fbg含量无显著性差别 (P >0 .0 5 )。结论 :高原青年移居者血液处于高凝状态。
Objective: To study the status of coagulation and fibrinolytic system of young migrants in plateau. Methods: The levels of plasma t-PA, PAI and Fbg in 38 young migrants were detected and compared with 36 healthy Tibetan Youth to compare. Plain healthy youth as a control. Results: The t-PA activity of immigrants was lower than that of the Tibetan native group and the control group (P <0.05), and the PAI activity was increased (P <0.05). There was no significant difference in the Fbg content among the groups > 0 .0 5). Conclusion: Plateau young settlers blood hypercoagulable state.