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PSS 是从褐藻提取的、经过处理并人工合成的多糖硫酸脂,其结构与肝素极相似,具有肝素样抗凝活性。为了进一步了解 PSS 的抗凝机理及其毒性反应,进而为临床应用提供科学依据,我们采用 PSS 注射液对家兔进行实验观察。现将其结果报告如下:材料和实验方法(一)材料:PSS 注射液。由山东海洋学院提供,每只2ml 含100毫克。每1毫克相当肝素30单位。
PSS is a polysaccharide sulphate extracted, processed and synthesized from brown algae and has a heparin-like structure with heparin-like anticoagulant activity. In order to further understand the anticoagulant mechanism of PSS and its toxic reaction, and then provide a scientific basis for clinical application, we used PSS injection on rabbits for experimental observation. The results are reported as follows: Materials and experimental methods (A) Material: PSS injection. Provided by Shandong Ocean University, each 2ml contains 100 mg. Each 1 mg is equivalent to 30 units of heparin.