多发性骨髓瘤(以下简称MM)是一种浆细胞异常增生的恶性肿瘤。此病过去比较少见,近年来报告日渐增多。典型病例诊断不难,但不典型或有并发症者,诊断则不易。由于本病实质上是一种非白血病性浆细胞白血病,故迄今无有效的治疗方法。因而本病的诊断和治疗仍有不少问题有待探讨。 Multiple myeloma (hereinafter referred to as MM) is a malignant tumor of abnormal proliferation of plasma cells. The disease was relatively rare in the past, and the reports have been increasing in recent years. Typical case diagnosis is not difficult, but not typical or complications, the diagnosis is not easy. As the disease is essentially a non-leukemia plasma cell leukemia, so far no effective treatment. Therefore, the diagnosis and treatment of the disease there are still many issues to be explored.