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目的:观察心复康口服液对正常及血瘀证大鼠血液流变学的影响,为其临床应用于气虚血瘀型充血性心力衰竭的治疗提供依据。方法:通过皮下注射肾上腺素及进行寒冷刺激复制大鼠血瘀证模型,观察不同剂量心复康口服液对血液流变学指标的影响。结果:心复康口服液对正常及血瘀证大鼠血液流变学的改善作用,可能是其应用于气虚血瘀型充血性心力衰竭的机制之一。
Objective: To observe the effect of Xinfukang oral liquid on hemorheology of rats with normal and blood stasis syndrome, and provide basis for clinical application of qi deficiency and blood stasis type congestive heart failure. Methods: The model of blood stasis was established by subcutaneous injection of epinephrine and cold stimulation to observe the effect of different doses of Xinfukang oral liquid on hemorheology. Results: The effect of Xinfukang oral liquid on hemorheology of normal and blood stasis rats may be one of the mechanisms of Xinfukang oral liquid used in congestive heart failure with qi deficiency and blood stasis type.