本文报道免做青霉素皮试口服美格西林片 10 5 5例患者不良反应观察结果。全部病例未发现过敏性休克及严重的过敏反应。与美格西林有关及可能有关的不良反应发生率为 0 19%。结果显示 ,美格西林安全有效 ,符合卫生部颁布的口服青霉素制剂质量检验标准 ,免做青霉素皮试用于临床是可行的 This article reports no-penicillin skin test of oral Metzirillin 105 patients with adverse reactions observed. All cases did not find anaphylactic shock and severe allergic reaction. The incidence of adverse reactions associated with and probably associated with mecicilin was 0 19%. The results showed that metacillin was safe and effective, in line with the Ministry of Health promulgated oral penicillin preparation quality inspection standards, free of penicillin skin test is feasible for clinical use