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目的分析尿石症患者的尿路结石化学成分及其分布特征。方法回顾性分析贵州省人民医院泌尿外科2009年12月至2012年9月共708例尿石症病例,以红外光谱法分析尿路结石的化学成分,并以患者性别、年龄、结石部位等为分组依据,分析各组尿路结石的化学成分特征。结果 40~<60岁组尿路结石发病率达高峰,男性与女性尿路结石患者的比率为1.97∶1;结石成分检出率最高的为草酸钙(占94.77%);其次是碳酸磷灰石(占38.70%),尿酸或尿酸铵(13.42%)、磷酸镁铵(3.53%)、磷酸氢钙(0.56%)、胱氨酸(0.28%)等成分结石所占比例较低。结论贵州省尿石症患者的尿路结石化学成分以草酸钙为主,草酸钙结石所占比率高于国内其他省份,有必要深入开展防治措施研究。
Objective To analyze the chemical composition and distribution of urolithiasis in patients with urolithiasis. Methods The urolithiasis of 708 cases of urolithiasis from December 2009 to September 2012 in Guizhou Provincial People’s Hospital were retrospectively analyzed. The chemical components of urinary calculi were analyzed by infrared spectroscopy. The gender, age, Group basis, analysis of the characteristics of the chemical composition of urinary tract stones in each group. Results The incidence of urolithiasis was highest in 40 ~ <60 years old group, and the ratio of urolithiasis was 1.97:1 in male and female patients. Calcium oxalate (94.77%) was the highest detection rate of stone components; Stone (accounting for 38.70%), uric acid or ammonium urate (13.42%), ammonium magnesium phosphate (3.53%), dicalcium phosphate (0.56%), cystine (0.28%) and other components of the lower proportion of stones. Conclusion The urolithiasis patients in Guizhou Province are dominated by calcium oxalate, and the proportion of calcium oxalate stones is higher than that in other provinces in China. Therefore, it is necessary to carry out prevention and treatment measures in depth.