论文部分内容阅读
目的：探讨基因药物与化疗药物联合用药对治疗肝肿瘤的疗效是否有增强效应。方法：将DOX插入到pORF-hTRAIL,形成pORF-hTRAIL-DOX复合物,多靶点不同机制联合治疗肝肿瘤，检测诱导细胞凋亡效率评价疗效。结果：联合给药诱导肿瘤凋亡效率显著高于单药组讨论相比单一基因治疗或者化学治疗，基因药物和化疗药物的联合治疗具有不可比拟的优势。“,”Objective To explore gene drugs and used in combination with chemotherapy drugs on the curative effect of treatment of liver tumor enhancement effect.Methods Insert DOX to pORF - hTRAIL, forming pORF - hTRAIL - DOX complex, multiple targets for different mechanism combination therapy of liver tumor and apoptosis induced by detecting efficiency, evaluation of curative effect.Results Joint drug induced apoptosis of tumor efficiency is significantly higher than single drug group.Conclusions Compared to a single gene therapy or chemical therapy, and chemotherapy drugs combination therapy, has the incomparable advantage.