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目的探讨多种肿瘤标志物在妇科肿瘤中的应用。方法选71例妇科肿瘤患者为观察组,另选70例同期健康体检者(均为女性)作为对照组;化学发光免疫法检测糖链抗原153(CA153)、糖链抗原199(CA199)、癌胚抗原(CEA)及癌抗原125(CA125)水平,比较各指标单一检测及联合检测阳性率。结果观察组CA153、CEA、CA125、CA199水平均高于对照组(P<0.05);各肿瘤标志物联合检测阳性率高于单一检测(P<0.05)。结论上述肿瘤标志物可作为诊治妇科肿瘤的依据,且各指标联合检测阳性率高。
Objective To explore the application of many tumor markers in gynecologic oncology. Methods 71 patients with gynecologic cancer were selected as the observation group and 70 healthy subjects (all female) as the control group. Chemiluminescent immunoassay was used to detect the expression of carbohydrate antigen 153 (CA153), carbohydrate antigen 199 (CA199), cancer Embryo antigen (CEA) and cancer antigen 125 (CA125) levels were compared between the single detection and the combined detection of positive rates. Results The levels of CA153, CEA, CA125 and CA199 in the observation group were significantly higher than those in the control group (P <0.05). The positive rate of the combined detection of tumor markers was higher than that of the single test (P <0.05). Conclusion The above tumor markers can be used as the basis for the diagnosis and treatment of gynecologic tumors, and the positive rate of the combined detection of each index is high.