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胃内容及(或)十二指肠内容返流入食管称为胃食管返流(gastroesophageal reflux,GER)。GER 在小儿十分常见,短暂的返流尤其在食后多为生理现象。频繁持续的返流可引起临床症状如呕吐、吸入性肺炎及窒息和病理损害,如返流性食管炎等,称病理性返流。如何较客观地判定返流的病理生理性质,进而指导临床治疗,是 GER 研究领域不断探索又尚未解决的重要课题之一。24小时食管 pH 动态监测被认为是诊断 GER 的金标准,但主要是针对酸性返流设计的,存在20%～30%的假阴性率。我们首先采用胃食管双 pH 监测技术诊断小儿十二指肠胃食管返流,现将研究结果并综合有关文献讨论如下。
The contents of the stomach and / or duodenum back into the esophagus is called gastroesophageal reflux (GER). GER is very common in children, short-term reflux, especially after eating mostly physiological phenomenon. Frequent reflux can cause clinical symptoms such as vomiting, aspiration pneumonia and asphyxia and pathological damage, such as reflux esophagitis, said pathological reflux. How to determine the pathophysiological characteristics of reflux more objectively, and then to guide clinical treatment, is one of the important topics that GER research area is constantly exploring and remains unresolved. 24-hour esophageal pH dynamic monitoring is considered the gold standard for the diagnosis of GER, but is primarily designed for acid reflux with a 20% to 30% false negative rate. We first use of gastroesophageal pH monitoring technology in diagnosis of duodenal gastroesophageal reflux, the results of the study and the relevant literature discussed below.