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目的:探讨莫西沙星与左氧氟沙星在治疗社区获得性肺炎中的临床效果比较。方法:选取来我院就诊的社区获得性肺炎患者100例,随机分为实验组和对照组各50例,其中实验组患者均给予莫西沙星的治疗,对照组患者均给予左氧氟沙星的治疗,两组患者分别治疗一周后,统计其临床总有效率及不良发应发生率,进行数据分析,对比两种药物的临床治疗效果。结果:实验组全部50例患者,临床总有效率为90.0%;对照组的全部50例患者,临床总有效率为76.0%。两组患者的临床总有效率比较,差异具有统计学意义(P<0.05)。实验组患者的不良反应发生率为10%,明显低于对照组患者的18%,结果具有可比性(P<0.05)。结论:莫西沙星与左氧氟沙星在治疗社区获得性肺炎的患者中,具有更高的临床总有效率,并且患者发生恶心,呕吐,皮疹等不良发应的发生率更低,可作为首选药物临床推广应用。
Objective: To investigate the clinical effect of moxifloxacin and levofloxacin in the treatment of community-acquired pneumonia. Methods: One hundred patients with community-acquired pneumonia who were treated in our hospital were randomly divided into experimental group and control group with 50 cases in each group, in which moxifloxacin was given in the experimental group and levofloxacin in the control group. After treatment for one week, the patients in each group were statistically analyzed for the total effective rate and the incidence of adverse reactions, and the data were analyzed to compare the clinical effects of the two drugs. Results: All 50 patients in the experimental group had a total effective rate of 90.0%. All 50 patients in the control group had a total effective rate of 76.0%. The total effective rate of two groups of patients, the difference was statistically significant (P <0.05). The incidence of adverse reactions in the experimental group was 10%, which was significantly lower than that in the control group (18%). The results were comparable (P <0.05). CONCLUSIONS: Moxifloxacin and levofloxacin have a higher overall clinical efficacy in patients with community-acquired pneumonia and have a lower prevalence of adverse reactions such as nausea, vomiting and rash and may be clinically recommended as the preferred drug application.