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目的检测婴儿在麻疹疫苗初免前的胎传抗体水平,探讨麻疹免疫方法的科学性。方法采用间接酶联免疫法检测婴儿的胎传麻疹抗体,并进行统计分析。结果检测婴儿在麻疹疫苗初免前的指尖末梢血305人份,麻疹抗体阳性254份,阳性率83.28%,阴性51份,阴性率16.72%。2011-2012年麻疹疫苗初免前婴儿发病6例,占发病总数的24%(6/25)。结论婴儿在麻疹疫苗初免前缺乏特异抗体是发生麻疹的重要影响因素,建议国家疾控中心等权威部门进一步开展研究,最大限度地降低发生麻疹的影响因素,确保稳步实现消除麻疹目标。
Objective To detect the level of fetal antibodies in infants before measles vaccine immunization and to explore the scientific method of measles immunization. Methods The indirect immunosorbent assay was used to detect the fetal measles antibody in fetuses and the statistical analysis was made. Results The detection of infants in the measles vaccine before the tip of the tip of peripheral blood 305 people, measles antibody positive 254, the positive rate of 83.28%, negative 51, the negative rate of 16.72%. In 2011-2012, 6 cases of pre-immunization measles vaccine were infants, accounting for 24% (6/25) of the total. Conclusion The lack of specific antibody in infants before measles vaccine immunization is an important influencing factor for measles. It is suggested that further research should be conducted by authorities such as the National Center for Disease Control and Prevention to minimize the impact of measles and to ensure the goal of measles elimination is steadily achieved.