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目的 :通过对乳腺癌前哨淋巴结 (SLN)活检 ,探讨其对腋淋巴结转移情况预测的准确性。方法 :采用亚甲蓝染料法对 4 0例乳腺癌行腋窝蓝染淋巴结活检 ,后行常规腋窝淋巴结清除 (ALND) ,两标本均送病理检查。结果 :全组 4 0例患者检出SLN 38例 ,2例未找到SLN ,检出率为 95 % ( 38/ 4 0 ) ,有 8例SLN为阳性 ,1例SLN为假阴性 ,腋窝淋巴结 (ALN)有 9例转移 ,SLN与ALN病理检查完全符合者 37例 ,准确率为 92 5 % ( 37/ 38) ;灵敏度为 88 9% ( 8/ 9) ;假阴性率为 11 1% ( 1/ 9)。结论 :亚甲蓝染色法能准确地鉴别SLN及预测乳腺癌腋窝淋巴结状态
Objective: To investigate the accuracy of predicting axillary lymph node metastasis by breast cancer SLN biopsy. Methods: The axillary lymph node biopsy was performed on 40 cases of breast cancer using methylene blue dye method, followed by routine axillary lymph node dissection (ALND). All the specimens were sent for pathological examination. Results: 38 cases of SLN were detected in 40 cases of SLN, 2 cases of SLN were not detected, the detection rate was 95% (38/40), 8 cases of SLN was positive, 1 case of SLN was false negative, axillary lymph nodes There were 9 cases with ALN and 37 cases with SLN and ALN respectively. The accuracy rate was 92.5% (37/38), the sensitivity was 88.9% (8/9), the false negative rate was 11.1% (1 / 9). Conclusion: methylene blue staining can accurately identify SLN and predict breast cancer axillary lymph node status