Octacosanol is purified by agitated short-path distillation (SPD). Effects of evaporation temperature,number of SPD steps in series and other distillation method on the octacosanol recovery and decomposition arestudied. Although the experimental results indicate some decomposition when the mixture of higher primaryaliphatic alcohols is distillated by SPD, SPD is still an effective method to purify octacosanol. It is concluded thatevaporation temperature affects greatly on the purity and recovery of octacosanol.