甜叶菊提取物在商业上作为甜味剂。曾报道甜叶菊提取物可引起全身的和肾血管扩张,引起利尿和尿钠排泄。为评估甜叶菊提取物对肾功能的作用,作者在抗利尿和水利尿条件下研究了甜叶菊提取物对肾脏水、钠和钾排泄的影响。Wistar 雄性大鼠分抗利尿组和水利尿组,每组10只动物。首先灌注林格溶液(由10%菊粉和2%对氨基马尿酸组成的等渗溶液),以测定总肾小球滤过率(GFR)和有 Stevia extracts are commercially used as sweeteners. Stevia extract has been reported to cause systemic and renal vasodilation, causing diuresis and natriuresis. To assess the effect of stevia extract on renal function, the authors studied the effects of stevia extract on renal water, sodium, and potassium excretion under conditions of antidiuretic and consumptive urine conditions. Wistar male rats were divided into antidiuretic group and water continuum group, 10 animals in each group. The Ringer’s solution (isotonic solution consisting of 10% inulin and 2% p-amino-hippuric acid) was perfused first to determine the total glomerular filtration rate (GFR) and