论文部分内容阅读
目的观察二甲双胍治疗多囊卵巢综合征的临床效果。方法将多囊卵巢综合征患者68例,根据数字随机法将其分为观察组和对照组各34例。对照组给予常规治疗,观察组在此基础上给予二甲双胍治疗,对比2组疗效及治疗后性激素及血脂水平。结果观察组治疗总有效率为91.18%高于对照组的70.59%,差异有统计学意义(P<0.05)。观察组治疗后睾酮(T)、促卵泡素(FSH)及黄体生成素(LH)、总胆固醇(TC)、甘油三酯(TG)水平低于对照组,高密度脂蛋白胆固醇(HDL)水平高于对照组,差异均有统计学意义(P<0.05)。结论二甲双胍治疗多囊卵巢综合征患者疗效显著,可显著改善患者性激素水平和血脂水平,值得临床推广应用。
Objective To observe the clinical effect of metformin in the treatment of polycystic ovary syndrome. Methods Sixty-eight patients with PCOS were divided into observation group (34 cases) and control group (34 cases) according to the digital random method. The control group was given routine treatment. The observation group was treated with metformin on the basis of the above. The curative effect and the level of sex hormone and blood lipid after treatment were compared. Results The total effective rate of observation group was 91.18% higher than that of control group (70.59%), the difference was statistically significant (P <0.05). The levels of testosterone, follicle stimulating hormone (FSH), LH, TC and TG in the observation group were lower than those in the control group after treatment, and the level of HDL was higher Control group, the difference was statistically significant (P <0.05). Conclusion Metformin treatment of patients with polycystic ovary syndrome significant effect, can significantly improve the level of sex hormones and blood lipid levels in patients, it is worth promoting the clinical application.