目的探讨气压治疗联合甲钴胺穴位注射治疗糖尿病周围神经病变的临床效果及对患者生存质量的影响。方法糖尿病周围神经病变住院患者80例随机分为对照组和实验组各40例,对照组采用常规方法治疗,实验组在常规治疗的基础上给予气压治疗及穴位注射,2组分别在治疗前及2周治疗结束后进行评价,比较2组治疗前后的神经传导速度、生存质量改善情况及临床疗效。结果治疗后,2组患者正中神经和腓神经的感觉、运动神经传导速度的差异具有统计学意义(P均<0.05)。治疗后,对照组17例显效,12例有效,11例无效,有效率为72%;实验组28例显效,7例有效,5例无效,有效率为88%。对照组生存质量Ⅰ级10例,Ⅱ级10例,Ⅲ级13例,Ⅳ级7例;实验组生存质量Ⅰ级22例,Ⅱ级6例,Ⅲ级6例,Ⅳ级6例。2组患者的临床效果和生存质量比较差异具有统计学意义(P均<0.05)。结论气压治疗联合穴位注射治疗糖尿病周围神经病变效果明显,患者的生存质量得到提高,值得推广。 Objective To investigate the clinical effect of pressure therapy combined with mecobalamin injection on diabetic peripheral neuropathy and its impact on the quality of life of patients. Methods Eighty hospitalized patients with diabetic peripheral neuropathy were randomly divided into control group and experimental group, 40 cases in each group. The control group was treated by conventional method. The experimental group was given bariatric and point injection on the basis of routine treatment. Two weeks after the end of treatment were evaluated, the two groups before and after treatment of nerve conduction velocity, quality of life improvement and clinical efficacy. Results After treatment, the sensory and motor nerve conduction velocities of median nerve and peroneal nerve in two groups were statistically significant (all P <0.05). After treatment, 17 cases were markedly effective in the control group, 12 cases were effective, 11 cases were ineffective and the effective rate was 72%. In the experimental group, 28 cases were markedly effective, 7 cases were effective, 5 cases were ineffective and the effective rate was 88%. The quality of life in the control group was 10 grade Ⅰ, 10 grade Ⅱ, 13 grade Ⅲ, and 7 grade Ⅳ. The quality of life in the control group was 22 grade Ⅰ, 6 grade Ⅱ, 6 grade Ⅲ, and 6 grade Ⅳ. The clinical effects and quality of life in two groups were statistically significant (all P <0.05). Conclusions The combination of barotrauma and pneumoperitoneum is effective in treating diabetic peripheral neuropathy. The quality of life of the patients is improved and it is worth popularizing.