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对30例支气管哮喘病儿口服卡慢舒溶液后,外周血T淋巴细胞亚群的变化进行了观察。结果表明,治疗前后OKT_3无显著性变化;OKT_4治疗后显著降低(P<0.01);OKT_8治疗后显著升高(P<0.01),OKT_4/OKT_8比值治疗后显著降低(P<0.01)。治疗效果30例中28例显效。提示卡慢舒能够明显改善支气管哮喘病儿的免疫功能,是一种良好的、值得推广的免疫调节剂。对该药的作用机制进行了重点讨论。
Changes of T lymphocyte subsets in peripheral blood were observed in 30 children with bronchial asthma after oral administration of card slow solution. The results showed that OKT_3 had no significant change before and after treatment; OKT_4 decreased significantly (P <0.01); OKT_8 increased significantly (P <0.01); OKT_4 / OKT_8 ratio decreased significantly after treatment (P <0.01). Treatment effect of 30 cases in 28 cases markedly. Suggest card slow Shu can significantly improve the immune function of children with bronchial asthma, is a good, worth promoting the immune regulator. The mechanism of action of the drug was discussed.