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目的:观察阿莫西林联合碳酸铝镁片和兰索拉唑治疗消化道溃疡的疗效和安全性。方法:将已被确诊的272例消化道溃疡患者随机分为治疗组和对照组,治疗组有140例患者,采用兰索拉唑+阿莫西林+碳酸铝镁片治疗,对照组有132例患者,采用兰索拉唑治疗。治疗周期为6周,观察两组患者在治疗4周和6周后的情况,统计药物治疗的有效率。结果:治疗组和对照组在治疗4周和治疗6周时的有效率同时期比较具有统计学差异,治疗组不良反应发生率高于对照组,差异有统计学意义,但总体上两组的不良反应都比较轻微,不会对后续治疗产生影响。结论:阿莫西林联合碳酸铝镁与兰索拉唑治疗消化道溃疡的疗效比较好,不良反应比较少。
Objective: To observe the efficacy and safety of amoxicillin combined with magnesium aluminum carbonate tablets and lansoprazole in the treatment of peptic ulcer. Methods: A total of 272 patients with peptic ulcer were randomly divided into treatment group and control group. 140 patients in the treatment group were treated with lansoprazole + amoxicillin + magnesium aluminum carbonate tablets, while 132 patients in the control group Patients, treated with lansoprazole. The treatment period was 6 weeks. The two groups were observed after 4 weeks and 6 weeks, and the effective rate of drug treatment was calculated. Results: The effective rates of the treatment group and the control group at 4 weeks and 6 weeks of treatment were statistically significant at the same period, and the incidence of adverse reactions in the treatment group was higher than that of the control group, but the difference was statistically significant. However, Adverse reactions are relatively minor, will not affect the follow-up treatment. Conclusion: The efficacy of amoxicillin combined with magnesium aluminum carbonate and lansoprazole in the treatment of peptic ulcer is better with fewer adverse reactions.