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据德国研究人员报道,在接受他汀类药物治疗的患者中,并未见到与急性 ST 段升高的心肌梗死(MI)后的阵发性室性心动过速(VT)发生相关联的死亡风险增加。负责该项研究的德国 Klinikum der Stadt Ludwig-shafen 的 Bernhard Rauch 博士在接受路透健康的记者采访时指出,这些数据证实所有的 ST 段升高的心肌梗死患者应用他汀类药物治疗的重要性。德国的大多数急性心肌梗死患者发病后接受他汀类药物治疗,但发病后一年的用药比例却下降到50%以下。Rauch 博士及其研究小组在近期的《欧洲心脏杂志》上刊文指出,新的研究提示他汀类药物的心脏保护作用有可能强于降胆固醇作用,包括使自主神经系统功能恢复正常以及改善心肌细胞的电反应稳定性。已有证据证实,他汀类药物可降低心律失常的发病危险;此项研究的目的就是确定他汀类药物治疗对 ST 段升高心肌梗死后伴阵发性室性心动过速患者死亡率增加的影响。研究人员强调指出,目前患者心肌梗死后所用药物包括肾上腺素能β-受体拮抗剂和他汀类药物,对阵发性室性心动过速的预
According to German researchers, deaths associated with paroxysmal ventricular tachycardia (VT) following acute myocardial infarction (MI) with elevated ST segment were not seen in patients receiving statin therapy Increased risk. Bernhard Rauch, PhD, of Klinikum der Stadt Ludwig-shafen, Germany, who was in charge of the study, told Reuters Health correspondents that the data confirm the importance of statin therapy in all ST-segment elevation myocardial infarction patients. Most patients with acute myocardial infarction in Germany after receiving statin therapy, but the proportion of one year after the onset of the drug fell below 50%. Rauch and his team recently published in the European Journal of Cardiology that the new study suggests that statin cardioprotection may be stronger than cholesterol-lowering effects, including normalizing autonomic nervous system function and improving cardiomyocytes The electrical stability of the reaction. Statins have been shown to reduce the risk of arrhythmia; the purpose of this study was to determine the effect of statin therapy on increased mortality in patients with ST-segment elevation myocardial infarction complicated with paroxysmal supraventricular tachycardia . The researchers emphasize that at present, the drugs used in patients after myocardial infarction include adrenergic β-adrenergic antagonists and statins, pre-paroxysmal supraventricular tachycardia