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72例老年性脑梗塞患者随机分为治疗组和对照组,两组患者均给予控制血压、降颅内压、改善脑水肿和营养脑神经等对症支持治疗,观察组给予黄芪注射液静脉滴注,并给予血栓通胶囊口服;对照组给予复方丹参注射液静脉滴注治疗,观察两组患者用药前后血浆粘度、全血低切粘度、全血高切粘度、纤维蛋白原和红细胞比容等血液流变学指标的变化,并对临床疗效进行评定。两组患者的血浆粘度、全血低切粘度、全血高切粘度、纤维蛋白原和红细胞比容治疗后较治疗前均有所改善,治疗组改善效果明显优于对照组,P<0.05差异有统计学意义;两组患者治疗后神经功能缺损评分均较治疗前有所下降,治疗组下降值较对照组多,P<0.05差异有统计学意义;治疗组总有效率91.67%,对照组总有效率77.78%,治疗组临床疗效显著优于对照组,P<0.05差异有统计学意义。黄芪注射液联合血栓通胶囊治疗老年性脑梗塞安全稳定,疗效确切。
72 cases of senile cerebral infarction were randomly divided into treatment group and control group, both groups were given control of blood pressure, decreased intracranial pressure, improve brain edema and nutrition brain symptomatic symptomatic and supportive treatment, the observation group given Astragalus injection intravenous drip , And given Xueshuantong Capsules orally; the control group given compound Danshen injection intravenous infusion of two groups of patients before and after treatment of plasma viscosity, low blood viscosity, whole blood high shear viscosity, fibrinogen and hematocrit and other blood Rheological indicators of change, and to assess the clinical efficacy. Plasma viscosity, whole blood low-shear viscosity, whole-blood high-shear viscosity, fibrinogen and hematocrit were improved in both groups before and after treatment, and the improvement in the treatment group was significantly better than that in the control group (P <0.05) There was statistical significance; two groups of patients after treatment, neurological deficit scores were lower than before treatment, the treatment group decreased more than the control group, P <0.05 difference was statistically significant; the total effective rate was 91.67% The total effective rate was 77.78%. The clinical efficacy of the treatment group was significantly better than that of the control group, P <0.05 was statistically significant. Astragalus injection combined with Xueshuantong capsule for the treatment of senile cerebral infarction safe and stable, the exact effect.