硫化氢(H2S)是继一氧化氮和一氧化碳之后新近发现的第三种内源性小气体信号分子,最新研究表明与多种消化、泌尿、呼吸系统疾病如非甾体类抗炎药所致的急性胃黏膜损伤、肠易激综合征、肝硬化、肺动脉高压、肺间质纤维化、慢性阻塞性肺疾病、糖尿病肾病、高血压肾病的发病有关。相关药物的研发与临床应用可能为这些疾病的治疗提供新的方向。 Hydrogen sulfide (H2S) is the third endogenous small gas signaling molecule newly discovered after nitric oxide and carbon monoxide. The latest research shows that with a variety of digestive, urinary, respiratory diseases such as non-steroidal anti-inflammatory drugs Of acute gastric mucosal injury, irritable bowel syndrome, cirrhosis, pulmonary hypertension, pulmonary fibrosis, chronic obstructive pulmonary disease, diabetic nephropathy, and hypertensive nephropathy. R & D and clinical application of related drugs may provide new directions for the treatment of these diseases.