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目的了解丰台区感染性腹泻细菌性病原谱和流行特征,为本地区细菌性腹泻防治提供依据。方法收集2010-2011年4-12月丰台区4家哨点医院肠道门诊腹泻患者的粪便标本675份,按照WS287-2008、WS/T9-1996、GB17012-1997和WS289-2008进行沙门菌、志贺菌、副溶血性弧菌、非O1、O139群霍乱弧菌4种常见肠道致病菌的检测,并分析其流行特征。结果从收集到的675份标本中共分离到196株致病菌,阳性率为29.04%。阳性菌中居首位的是副溶血性弧菌,占40.31%(39/196),其次为志贺菌,占18.37%(36/196)。检出的志贺菌以宋内志贺菌为优势血清型。病原菌的检出具有明显的季节性,6-9月份检出率较高。不同年龄组之间检出率差异有统计学意义(P<0.05),性别间检出率差异无统计学意义(P>0.05)。结论丰台区细菌性腹泻病原主要以副溶血性弧菌为主,应有针对性的主动加强监测,尤其是高发季节。
Objective To understand the bacterial etiology and epidemiology of infectious diarrhea in Fengtai district and provide basis for the prevention and treatment of bacterial diarrhea in this area. Methods A total of 675 stool specimens of patients with diarrhea in four sentinel hospitals in Fengtai District from April to December in 2010-2011 were collected. According to WS287-2008, WS / T9-1996, GB17012-1997 and WS289-2008, Shigella, Vibrio parahaemolyticus, non-O1, O139 Vibrio cholerae four kinds of common intestinal bacteria detection, and analysis of its epidemiological characteristics. Results A total of 196 pathogenic bacteria were isolated from 675 samples collected, the positive rate was 29.04%. Positive bacteria in the first place is Vibrio parahaemolyticus, accounting for 40.31% (39/196), followed by Shigella, accounting for 18.37% (36/196). Shigella detected in Shigella sonnei dominant serotypes. Pathogen detection has obvious seasonal, 6-September detection rate is higher. There were significant differences in the detection rates among different age groups (P <0.05). There was no significant difference in the detection rates among the sexes (P> 0.05). Conclusion The main pathogen of bacterial diarrhea in Fengtai District is Vibrio parahaemolyticus, which should be monitored actively, especially in high season.