目的:制备右旋布洛芬搽剂并观察其临床疗效。方法:以甘油、聚乙二醇-400为辅料,月桂氮(?)酮为透皮吸收促进剂,制备右旋布洛芬搽剂,同时观察临床疗效。结果:右旋布洛芬线性范围为10～70μg·ml-1(r=0.999 8),平均回收率为100.2%,RSD 1.20%。63例患者总有效率为92.10%。结论:该搽剂处方合理,质控方法可靠,临床疗效较好。 Objective: To prepare ibuprofen liniment and observe its clinical efficacy. Methods: Glycerol, polyethylene glycol-400 as excipients and lauryl (?) Ketone as transdermal absorption promoter were used to prepare ibuprofen liniment, and the clinical efficacy was observed. Results: The linear range of dexibuprofen was 10-70μg · ml-1 (r = 0.999 8). The average recovery was 100.2% and the RSD was 1.20%. The total effective rate of 63 patients was 92.10%. Conclusion: The liniment prescription is reasonable, quality control method is reliable, the clinical curative effect is better.