先天性结核病极为罕见,目前世界上报道过的不足300例,国内报道亦寥寥可数。本院曾收治一例,现报告如下:患儿女,18天,因皮肤脓疱疹7天,发热5天于1989年7月20日入院。患儿为第一胎,孕期37周,出生情况良好,体重2700克,母亲在妊娠后期曾反复发热,产前两天高热不退,产后第二天被确诊为粟粒型肺结核即被隔离治疗,故产后未与患儿有过接触。生后第11天患儿皮肤出现脓疮疹,第14天开始发热,体温37.5℃至38.8℃。食欲不佳体重不增。生后第四天按种卡介苗。门诊拟新生儿脓疱疹,新生儿肺炎收入院。体检:T38.8℃,HR162次/分,R62次/分,体重2700克,皮肤有散在性脓疱疹,表浅淋巴结不大,前囱平软,颈无抵抗,心肺无异常特征,肝肋下2cm,脾肋下1.5cm。化验检查:外周血白 Congenital tuberculosis is extremely rare, currently less than 300 cases reported in the world, the domestic reports are also very few. The hospital had admitted a case, the report is as follows: Children, 18 days, due to skin pustules 7 days, fever 5 days in July 20, 1989 admission. Children with a first child, 37 weeks of pregnancy, a good birth, weight 2700 grams, the mother had repeated fever in the second trimester of pregnancy, fever two days before delivery, was diagnosed the second day postpartum miliary tuberculosis was isolated treatment, Therefore, children have not been exposed after contact with children. Children born on the 11th day after birth purulent sores rash, the first 14 days fever, body temperature 37.5 ℃ to 38.8 ℃. Poor appetite weight does not increase. The fourth day after birth by BCG. Outpatient quasi-neonatal impetigo, neonatal pneumonia income hospital. Physical examination: T38.8 ℃, HR162 beats / min, R62 beats / min, weight 2700 grams, the skin has scattered impetigo, superficial lymph nodes is not large, before the chimney soft, neck no resistance, no abnormal heart and lung characteristics, liver ribs Under 2cm, spleen rib 1.5cm. Laboratory tests: white blood