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目的: 观察复方蒿甲醚片治疗间日疟疗效的影响。方法:用复方蒿甲醚片(每片含苯芴醇 120 m g、蒿甲醚 20 m g)16 片3 d 分服( A 组)、20 片5 d 分服( B组),氯喹伯氨喹8 日疗法( C对照组)三组分别治疗36 例、41 例和 55 例。结果: A、 B、 C三组的平均退热时间相近,分别为 22.3 h、23.2 h 和25.0 h;平均原虫转阴时间为33.5 h、30.5 h 和44.9 h; A、 B两组均显著快于 C组( P< 0.01)。治后9 个月的临床复发率: A、 B、 C组各为84.9% 、78.8%和 22.9% ; A、 B组均显著高于 C组( P均< 0/01)。结论:两种治疗方案治疗间日疟均具有速效。
Objective: To observe the effect of compound artemether on the curative effect of Plasmodium vivax. Methods: The tablets of artemether (each tablet containing lumefantrine 120 m g and artemether 20 m g) for 16 days were divided into three groups (group A), 20 groups for 5 days (group B), chloroquine Primary primaquine 8-day treatment (C control group) were treated 36 cases, 41 cases and 55 cases. Results: The average antipyretic time of groups A, B and C were similar, which were 22.3 h, 23.2 h and 25.0 h, respectively. The mean time of negative protozoa was 33.5 h, 30.5 h and 44 .9 h; A, B both groups were significantly faster than C group (P <0.01). The clinical recurrence rates at 9 months after treatment were 84.9%, 78.8% and 22.9% in groups A, B and C, respectively, and those in groups A and B were significantly higher than those in group C (all P <0/01 ). Conclusion: Both treatments are effective against P. vivax.