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目的了解住院肺炎病例军团菌感染状况及类型。方法调查供水系统受军团菌污染的某医院的90例住院肺炎病例,通过问卷调查、深部痰液军团菌培养和荧光定量PCR检测、军团菌尿抗原和血抗体检测,确定军团菌发病情况及类型。结果住院肺炎病例中军团菌肺炎阳性率15.6%,其中痰培养和PCR检测均为阳性1例,仅尿抗原阳性13例;社区获得性军团菌肺炎16.4%,医院获得性军团菌肺炎13.0%。结论该医院住院肺炎病例存在军团菌感染,社区获得性和医院获得性军团菌肺炎均有发病。
Objective To understand the status and types of Legionella infection in hospitalized pneumonia. Methods Ninety cases of hospitalized pneumonia in a hospital contaminated by Legionella by water supply system were investigated. Questionnaires, Legionella pneumophila culture and quantitative PCR, Legionella pneumophila antigen and blood antibody were used to determine the incidence and type of Legionella . Results The positive rate of Legionella pneumonia in hospitalized pneumonia was 15.6%, of which 1 was positive in sputum culture and PCR and 13 in urine. Only 16.4% of community-acquired Legionella pneumonia and 13.0% of hospital-acquired Legionella pneumonia were detected. Conclusions There are Legionella infections in hospital-acquired pneumonia cases, community-acquired and hospital-acquired Legionella pneumonia.