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目的探讨振源胶囊对无症状心衰(心力衰竭)患者6min步行距离、左室射血分数、左室内径、发展为显性心衰者等指标的影响。方法 52例患者分为两组,对照组为使用洛汀新(贝拉普利)治疗,治疗组加用振源胶囊治疗。结果两组干预措施均可不同程度改善6min步行距离、左室射血分数、左室收缩末期内径,且治疗组改善左室射血分数较对照组差异有统计学意义。左室舒张末期内径及发展为显性心衰者两组差异无统计学意义。结论振源胶囊具有改善无症状心衰患者心功能(6min步行距离、左室射血分数、左室收缩末期内径)的作用,对左室舒张末期内径无影响。
Objective To investigate the effect of Zhenyuan Capsule on 6-minute walk distance, left ventricular ejection fraction, left ventricular internal diameter, and development of dominant heart failure in patients with asymptomatic heart failure (heart failure). Methods 52 patients were divided into two groups, the control group was treated with Lotensin (berapril), and the treatment group was treated with Zhenyuan Capsule. Results Both interventions could improve walking distance, left ventricular ejection fraction and left ventricular end-systolic diameter in varying degrees. There was significant difference between the two groups in the improvement of left ventricular ejection fraction in the treatment group as compared with the control group. Left ventricular end-diastolic diameter and the development of dominant heart failure, there was no significant difference between the two groups. Conclusion Zhenyuan Capsule has the effect of improving cardiac function (6min walking distance, left ventricular ejection fraction and end-systolic diameter) in patients with asymptomatic heart failure and has no effect on the end-diastolic diameter of left ventricle.