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对61位有消化道症状,经胃电图,胃十二指肠气钡双重造影或胃镜证实为胃炎、十二指肠炎或消化性溃疡的病儿及其家庭成员,用ELISA检测血清幽门螺旋菌抗体。在40例HP(+)的患儿中,有36个家庭存在血清HP抗体(占90%);总共检测121个家庭成员,HP(+)有108人(占89.26％),而21例HP(-)的患儿中,仅11个家庭成员存在HP抗体(52.26％),总共检测54个家庭成员,13人有HP(+)(24.07％)。两组结果有显著差异,证实了HP感染的家庭内群集性,提示了HP感染存在人——人传播或家庭成员共同暴露于同一传染源的可能性。
Sixty-one children with gastrointestinal symptoms, gastric electrogastrogram, double gastroduodenal barium double gastroscopy or gastroscopy confirmed as gastritis, duodenal inflammation or peptic ulcer children and their family members, serum Helicobacter pylori Antibodies. Thirty-six of the 40 children with HP (+) had serum HP antibody (90%); a total of 121 family members were detected, with 108 (89.26%) HP (+) and 21 (-) had only HP antibody (52.26%) in 11 family members, a total of 54 family members and 13 (24.07%) of 13 family members. Significant differences between the two groups confirmed the in-household clustering of HP infection, suggesting the possibility of HP-exposure to human-human transmission or family members co-exposure to the same source of infection.