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目的 探讨合并门脉高压症的重度肝硬化肝癌的治疗方法。方法 对 48例合并门脉高压症重度肝硬化肝癌在肿瘤TNM临床分期 (CTNM)诊断的基础上 ,分别采用联合切除手术治疗、姑息切除术后插管化疗、肝动脉介入治疗及全身化疗等不同治疗方法。结果 经上述多途径分类治疗后 ,48例均获得较为满意的临床疗效。尤其是 6例不能手术切除的巨大重度肝硬化肝癌患者在经肝动脉介入治疗后 ,获得再手术机会成为一个有希望的治疗模式。结论 外科手术治疗的疗效仍居各种疗法之冠 ,对于失去手术机会的中、晚期重度肝硬化肝癌 ,肝动脉介入治疗是首选方法。
Objective To investigate the treatment of hepatocellular carcinoma of the liver with severe cirrhosis complicated with portal hypertension. Methods Forty-eight patients with hepatocellular carcinoma of the liver with severe cirrhosis of portal hypertension were divided into three groups based on the diagnosis of TNM stage (CTNM), surgical treatment of joint resection, intubation chemotherapy after palliative resection, interventional chemotherapy of hepatic artery and systemic chemotherapy treatment method. Results After the above multi-channel classification treatment, 48 cases were more satisfied with the clinical efficacy. In particular, 6 cases of unresectable patients with huge, severe cirrhosis of liver cancer receiving reoperation after hepatic artery intervention become a promising treatment modality. Conclusion The efficacy of surgical treatment is still the highest of all kinds of therapies. Interventional treatment of hepatic artery is the preferred method for the treatment of advanced hepatocellular carcinoma with severe cirrhosis and loss of surgical opportunity.