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将 6 33例中晚期食管癌患者随机分为三组进行治疗 ,A组单纯手术 ,B组术前放疗 +手术 ,C组术前放疗、休息 2周后手术、术后辅以化疗。结果显示 ,A组肿瘤切除率低于 B、 C组 (P<0 .0 5 ) ;术后死亡率、并发症三组无明显差异 (P>0 .0 5 ) ;2年生存率三组相近 (P>0 .0 5 ) ,3年生存率 A组低于 B、C组 (P<0 .0 5 ) ,5年生存率 A、 B组相近 (P>0 .0 5 ) ,但均低于 C组 (P<0 .0 5 )。提示对中晚期食管癌宜选择手术为主的综合治疗 ,本文推荐术前放疗 +手术 +术后化疗。
Sixty-three patients with advanced esophageal cancer were randomly divided into three groups for treatment. Group A was operated on alone. Group B received preoperative radiotherapy plus surgery. Group C received preoperative radiotherapy. After 2 weeks’ rest, they were treated with chemotherapy and followed by chemotherapy. The results showed that the tumor resection rate in group A was lower than that in group B and C (P <0.05). There was no significant difference in postoperative mortality and complications among the three groups (P> 0.05) (P> 0.05). The 3-year survival rate in group A was lower than that in group B and C (P <0.05), and the 5-year survival rate was similar in group A and B (P> 0.05) Were lower than those in group C (P <0.05). Tip of the advanced esophageal cancer should choose surgery-based comprehensive treatment, this article recommended preoperative radiotherapy + surgery + postoperative chemotherapy.