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高血压患者经联合3种足量降压药物治疗(其中包括利尿剂)后血压仍不能降到140/90毫米汞柱以下,或者老年单纯收缩期高血压不能使收缩压降低至160毫米汞柱以下者,诊断为顽固性高血压。这是根据Kaplan和JNCVI(1997)的诊断标准做出的诊断。顽固性高血压的患病率在治疗的高血压人群中约占3%～29%,在专科就诊的患者中可能高达25%～30%。顽固性高血压可增加心肌梗死、脑卒中、心衰、肾衰等并发症的发生。
Blood pressure does not drop below 140/90 mmHg after hypertensive patients have been treated with 3 full-scale antihypertensive drugs, including diuretics, or elderly systolic hypertension can not reduce systolic blood pressure to 160 mmHg The following, the diagnosis of refractory hypertension. This is a diagnosis based on the diagnostic criteria of Kaplan and JNCVI (1997). The prevalence of refractory hypertension accounts for about 3% to 29% of the hypertensive population treated, and may be as high as 25% to 30% in specialist care. Refractory hypertension can increase the incidence of myocardial infarction, stroke, heart failure, renal failure and other complications.