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目的 :评价甘草对口腔溃疡的治疗效果。方法 :建立动物口腔溃疡模型 ,采用随机对照的研究方法 ,将 3 0只豚鼠分为空白对照组、锡类散治疗组和甘草散治疗组 ,每组各 10只动物。在治疗后第 5d观察溃疡直径的变化、溃疡周围的充血程度及溃疡表面的感染情况。结果 :治疗前溃疡直径三组间比较无显著性差异。治疗后第 5d甘草散组的溃疡直径亦明显小于锡类散组和空白对照组。溃疡周围充血程度及表面感染情况亦明显轻于其它两组。结论 :甘草散对治疗口腔溃疡疗效较好。
Objective: To evaluate the curative effect of licorice on oral ulcers. METHODS: Animal oral ulcer models were established. Randomized controlled study methods were used to divide 30 guinea pigs into blank control group, tin type powder treatment group, and licorice powder treatment group, with 10 animals in each group. At the 5th day after the treatment, the change of the ulcer diameter, the degree of congestion around the ulcer, and the infection of the ulcer surface were observed. Results : There was no significant difference in the diameter of the ulcer before the treatment among the three groups. The diameter of ulcers in the Glycyrrhiza granulosus group at the 5th day after treatment was also significantly smaller than that of the tin group and the blank control group. The degree of congestion around the ulcer and the surface infection were also significantly lighter than the other two groups. Conclusion :Licorg San has a good effect on the treatment of oral ulcers.