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目的探索广东省特定人群野生动物接触与SARS冠状病毒感染的关系。方法采用ELISA法和间接免疫荧光试验(IFA)联合检测野生动物接触人群血清SARS冠状病毒IgG抗体(SARS-IgG),以判断SARS冠状病毒感染情况;用非条件logistic回归分析野生动物接触与SARS冠状病毒感染之间的关系。结果单因素非条件logistic回归分析结果表明,接触山猪、黄犭京、果子狸、蛇、穿山甲、巨蜥、猴和山鸡是SARS冠状病毒感染的可疑危险因素,OR值分别为5.81(P=0.000)、4.64(P=0.000)3、.31(P=0.000)、1.93(P=0.039)、12.98(P=0.029)、19.89(P=0.001)、11.05(P=0.001)和2.21(P=0.018);与非野生动物从业人员相比,从事野生动物销售、果子狸饲养和在经营野生动物酒家从事野生动物相关职业是SARS冠状病毒感染的可疑危险因素,OR值分别为31.55(P=0.001)、14.32(P=0.018)和8.14(P=0.043);多因素非条件logistic回归分析结果表明,接触山猪和果子狸是SARS冠状病毒感染的可疑危险因素,OR值分别为4.97(P=0.002)和2.95(P=0.022);与非野生动物从业人群相比,从事野生动物销售是SARS冠状病毒感染的可疑危险因素,OR值为31.99(P=0.004)。结论从事野生动物销售可能增加SARS冠状病毒感染机会;山猪和果子狸是广东省SARS冠状病毒感染的可能来源。
Objective To explore the relationship between wildlife exposure and SARS-CoV infection in specific populations in Guangdong Province. Methods ELISA and indirect immunofluorescence assay (IFA) were used to detect SARS-CoV IgG antibody in SARS-IgG to detect SARS-CoV infection. Non-conditional logistic regression was used to analyze the relationship between SARS coronavirus The relationship between virus infection. Results The results of univariate logistic regression showed that Susceptible risk factors for SARS-CoV infection were contact with wild boar, Huangpijing, civet cat, snake, pangolin, monitor lizard, monkey and pheasant, with OR values of 5.81 (P = 0.000 ), 4.64 (P = 0.000), 3.31 (P = 0.000), 1.93 (P = 0.039), 12.98 (P = 0.029), 19.89 0.018). Compared with non-wildlife workers, wildlife engaged in wildlife sales, civet cats and wildlife related wildlife operators were suspicious risk factors for SARS-CoV infection with ORs of 31.55 (P = 0.001 ), 14.32 (P = 0.018) and 8.14 (P = 0.043) respectively. Multivariate non-conditional logistic regression analysis showed that contact with wild boar and civet cats were suspicious risk factors for SARS-CoV infection with OR values of 4.97 (P = 0.002) and 2.95 (P = 0.022). Wild animal sales were suspicious risk factors for SARS-CoV infection, with an OR of 31.99 (P = 0.004) compared to non-wildlife workers. Conclusion Engaging in wildlife sales may increase the chances of SARS-CoV infection. Pigs and civets are potential sources of SARS-CoV infection in Guangdong Province.