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目的:探讨中度及重度烧伤合并四肢骨折的诊治方法及其对IL-6的影响。方法:选择2009年10月～2012年10月我院收治的中度及重度烧伤合并四肢骨折患者60例,都采用基础治疗结合自体植皮术。结果:随着治疗时间的推移,患者创面愈合率逐渐增加,不同时间点对比差异明显(P<0.05)。治疗后的IL-6值明显少于治疗前,不同时间点对比差异明显(P<0.05)。结论:中度及重度烧伤合并四肢骨折病情比较危重,自体皮移植治疗能提高创面愈合率,可能与改善炎症因子表达有关。
Objective: To investigate the diagnosis and treatment of moderate and severe burns with limb fractures and its impact on IL-6. Methods: From October 2009 to October 2012, 60 patients with moderate and severe burn complicated with extremities fractures admitted in our hospital were treated with autologous skin grafting. Results: With the increase of treatment time, wound healing rate of patients gradually increased, with significant difference at different time points (P <0.05). After treatment, the value of IL-6 was significantly less than before treatment, with significant difference at different time points (P <0.05). Conclusion: The moderate and severe burns complicated with extremities fractures are more critical. Autologous skin grafting can improve the wound healing rate, which may be related to the improvement of the expression of inflammatory cytokines.