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目的:分析四川某社区卫生服务中心药品不良反应,为临床安全用药提供参考依据。方法:选取四川某社区卫生服务中心在2011年6月至2014年6月期间的药品不良反应106例作为研究对象,采用回顾性分析的方法,分析药品不良反应的影响因素以及规律和特征。结果:106例药品不良反应中男性患者51例(48.11%),女性患者55例(51.89%),男女患者差异不大,且不具备统计学意义(P>0.05);药品不良反应的患者年龄在8-86岁之间,其中年龄超过60岁的患者36例(33.96%),且随着年龄的增加,药品不良反应发生的概率越大;药品不良反应涉及的药品主要包括抗感染药物58例(54.72%)、中药类30例(28.30%)、呼吸系统药物3例(2.83%)、消化系统药物4例(3.77%)、泌尿系统药物1例(0.95%)以及其他不良反应10例(9.43%)。结论:药品不良反应的原因较多,年龄、药物种类等都可能引起药品不良反应,社区卫生服务中心要加以重视,减少药品不良反应的发生。
Objective: To analyze the adverse drug reactions of a community health service center in Sichuan and provide a reference for the clinical use of drugs. Methods: A total of 106 cases of adverse drug reactions in a community health service center in Sichuan from June 2011 to June 2014 were selected as research subjects. The influencing factors, regularities and characteristics of adverse drug reactions were analyzed by retrospective analysis. Results: There were 51 males (48.11%) and 55 females (51.89%) in 106 cases of adverse drug reactions. There was no significant difference between male and female patients (P> 0.05). The age of adverse drug reactions Among the patients aged 8-86 years, 36 cases (33.96%) were over 60 years of age, and the greater the probability of adverse drug reactions with age, the drugs involved in adverse drug reactions mainly included anti-infective drugs (54.72%), 30 cases of traditional Chinese medicine (28.30%), 3 cases of respiratory system drugs (2.83%), 4 cases of digestive system drugs (3.77%), 1 case of urinary system drugs (0.95%) and 10 cases of other adverse reactions (9.43%). Conclusion: There are many reasons for adverse drug reactions, such as age and type of drugs, which may cause adverse drug reactions. Community health service centers should pay attention to reduce the occurrence of adverse drug reactions.