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药物因素 药物的剂量、剂型、给药途径和制剂工艺等,均可明显影响药物的作用。 1、量效关系 剂量与效应的关系称为量效关系,常用量效曲线来表示。量效曲线说明量效关系存在下述规律:(1)药物必须达到一定的剂量才能产生效应;(2)在一定范围内,剂量增加效应也增强;(3)效应的增加并不是无限制的,而有一定的限度,这个极限称为最大效应或效能,达到最大效应后,剂量再增加效
Drug factors Drug dosage, dosage form, route of administration and preparation process, can significantly affect the role of drugs. 1, the dose-effect relationship The relationship between dose and effect is called the dose-effect relationship, commonly used dose-response curve to represent. The dose-response curve shows the following rules for the dose-effect relationship: (1) the drug must reach a certain dose to produce the effect; (2) the dose-increasing effect is also increased within a certain range; (3) the effect is not unlimited , And there is a certain limit, this limit is called the maximum effect or efficacy, to maximize the effect, the dose increases again and again