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目的:评价甲泼尼龙冲击治疗多发性硬化的应用效果。方法:随机抽取2013年1月至2016年12月南阳市第二人民医院收治的60例多发性硬化患者设作研究对象,根据随机数字表法将60例患者分成两组,抽取其中的30例患者仅应用丙种球蛋白治疗设作对照组,余下的30例患者在丙种球蛋白治疗基础上增加甲泼尼龙冲击治疗设作观察组,比较两组治疗效果和不良反应。结果:治疗后,观察组治疗总有效率96.67%,对照组治疗总有效率80.00%,两组疗效比较,差异具有统计学意义(P<0.05);观察组不良反应发生率10.00%,对照组不良反应发生率6.67%,两组不良反应比较,差异无统计学意义(P>0.05)。结论:多发性硬化应用甲泼尼龙冲击治疗安全性较高,而且不良反应较少。
Objective: To evaluate the application of methylprednisolone in the treatment of multiple sclerosis. Methods: A total of 60 patients with multiple sclerosis admitted to the Second People’s Hospital of Nanyang from January 2013 to December 2016 were randomly assigned to study. According to the random number table, 60 patients were divided into two groups, of which 30 The patients were only treated with gamma globulin as the control group. The remaining 30 patients were treated with methylprednisolone as the observation group on the basis of gamma globulin treatment. The treatment effects and adverse reactions were compared between the two groups. Results: After treatment, the total effective rate was 96.67% in the observation group and 80.00% in the control group, the difference was statistically significant (P <0.05); the incidence of adverse reactions in the observation group was 10.00% The incidence of adverse reactions was 6.67%. There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Multiple sclerosis with methylprednisolone shock treatment is safe and has few adverse reactions.