论文部分内容阅读
目的探讨幽门螺杆菌（Ｈｐ）感染与胃癌的关系。方法在世界胃癌最高发区之一—福建省长乐市进行１∶１配对病例对照研究，用ＥＬＩＳＡ方法检测血清抗Ｈｐ的ＩｇＧ抗体。结果研究对象中Ｈｐ阳性总检出率为６３６８％，病例和对照Ｈｐ感染率的差异无显著意义（Ｐ＞００５）。胃腺癌病例Ｈｐ感染率为６８１８％。贲门部胃癌Ｈｐ感染率为５６００％。胃癌高发区Ｈｐ感染率高。结论Ｈｐ感染与长期摄入鱼露、少吃新鲜蔬菜和不良饮食习惯等因素相互作用，胃癌发生的危险性增高。
Objective To investigate the relationship between Helicobacter pylori (Hp) infection and gastric cancer. METHODS: A 1:1 matched case-control study was conducted in Changle City, Fujian Province, one of the highest cancer areas in the world, and IgG antibodies against Hp were detected by ELISA. RESULTS: The total positive rate of Hp was 63.8% in the study subjects, and there was no significant difference between the cases and control Hp infection rates (P>0.05). The incidence of Hp infection in gastric adenocarcinoma was 68% and 18%. The gastric cancer Hp infection rate in the gastric cardia was 56.0%. High incidence of Hp infection in gastric cancer is high. Conclusion Hp infection interacts with long-term intake of fish sauce, eating less fresh vegetables and poor dietary habits, and the risk of gastric cancer increases.