肌萎缩侧索硬化(ALS)为运动神经元病最常见的类型,其诊断除了依据临床表现外,主要依据神经电生理检查结果。其他辅助检查如肌酸磷酸激酶(CK)活性可轻度异常,头颅MRI可能显示部分病例受累脊髓和脑干萎缩变小,脑脊液检查、血生化、 Amyotrophic lateral sclerosis (ALS) is the most common type of motor neuron disease and its diagnosis is based primarily on neurophysiological findings, in addition to its clinical manifestations. Other ancillary tests such as creatine phosphokinase (CK) activity may be mild abnormalities, and cranial MRI may show that in some cases the atrophy of the affected spinal cord and brainstem diminishes, cerebrospinal fluid tests, blood biochemistry,