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[目的]了解上海市奉贤区出生缺陷发生情况、分布特征及变化趋势。[方法]采用回顾性分析2008—2010年奉贤区出生缺陷人群监测资料(孕28周至产后42 d)。[结果]监测围产儿总数15 744例,缺陷数277例,出生缺陷率分别为138.94/万,162.28/万,230.66/万,3年发生率有上升趋势。主要缺陷种类顺位依次为先天性心脏病、外耳畸形、脐疝、多指(趾)、并指(趾)、唇腭裂、血管瘤、先天性脑积水、神经管缺陷。[结论]近年来出生缺陷率上升需得到重视,应继续加强监测工作,加强出生缺陷综合防控。
[Objective] To understand the occurrence, distribution characteristics and trend of birth defects in Fengxian District of Shanghai. [Methods] The surveillance data of birth defects in Fengxian District from 2008 to 2010 (28 gestational weeks to 42 days postpartum) were retrospectively analyzed. [Results] The total number of perinatal monitoring of 15 744 cases, the number of defects 277 cases, the birth defect rates were 138.94 / million, 162.28 / million, 230.66 / million, 3-year incidence has an upward trend. The order of the main defects followed by congenital heart disease, external ear deformity, umbilical hernia, multiple fingers (toes), and the fingers (toe), cleft lip and palate, hemangioma, congenital hydrocephalus, neural tube defects. [Conclusion] In recent years, the birth defect rate needs to be paid more attention. The monitoring work should be strengthened and the comprehensive prevention and control of birth defects should be strengthened.