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粒细胞性肉瘤(granulocytic sarcoma)是一种由幼稚粒细胞形成的髓外局灶性实体肿瘤。临床上主要发生在以下3种情况。①作为急性髓细胞性白血病的先兆,而骨髓和血液并无白血病证据;②与骨髓增生症合并,通常临近于慢粒急变期或其他类型骨髓增生症的白血症转化期;③作为急性髓细胞性白血病的髓外表现。由于其临床表现较罕见和特殊,尤其是当骨髓和血液尚不能诊断白血病时,常常导致临床误诊。本文就粒细胞性肉瘤的有关问题综述如下。 1811年Burns最先描述了1例病人患有凸眼后眼眶、泪腺、鼻副窦绿色实体性肿块。1853年King观察到类似的病人,并将这
Granulocytic sarcoma is an extramedullary focal solid tumor formed by immature granulocytes. Clinically occurs in the following three cases. ① as a precursor of acute myeloid leukemia, and bone marrow and blood leukemia is no evidence; ② combined with myeloproliferative disease, usually near the blast crisis or other types of myeloproliferative leukemia transformation; ③ as acute myeloid Extramedullary leukemia manifestations. Clinical misdiagnosis often results from its rare clinical appearance and specificity, especially when bone marrow and blood are not yet diagnosed with leukemia. This article on the relevant issues of granulocytic sarcoma are summarized below. Burns first described in 1811 a patient suffering from a retropubic orbital, lacrimal gland, nasal sinus green solid mass. In 1853 King observed a similar patient and took this