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食物依赖性库欣综合征是近年新发现的库欣综合征的一种罕见类型。其病因为肾上腺组织中过度表达 (或异位表达 )抑胃肽受体 ,对进食后生理性分泌的抑胃肽产生异常反应。肾上腺病理变化多为双侧大结节性增生 ,也可为单侧腺瘤。药物 (奥曲肽 )治疗难以获得满意疗效。手术切除双侧或单侧肾上腺可使病情缓解。
Food dependence Cushing’s syndrome is a rare type of Cushing’s syndrome newly discovered in recent years. The etiology is due to overexpression of adrenal tissue (or ectopic expression) inhibition of gastric peptide receptors, the physiological secretion of gastric inhibitory peptide abnormal reaction. Adrenal pathological changes mostly bilateral nodular hyperplasia, but also for unilateral adenoma. Drug (octreotide) treatment is difficult to obtain satisfactory results. Surgical removal of bilateral or unilateral adrenal can make the condition eased.