米非司酮作为一种孕激素拮抗剂 ,广泛应用于临床 ,与前列腺素配伍终止早孕在国内外普遍开展 ,有效率在 93%～ 95 %之间。其作用机制是在受体水平拮抗孕激素的生物学效应 ,从而引起胚胎及其支持组织在代谢和形态结构方面发生一系列改变 ,最终导致流产[1] 。本文仅就米非司酮药物 As a kind of progestin antagonist, mifepristone is widely used clinically, and the compatibility of prostaglandin with early termination of pregnancy is generally carried out at home and abroad, the effective rate is between 93% and 95%. Its mechanism of action is to antagonize the biological effects of progesterone at the receptor level, causing a series of changes in the metabolism and morphological structure of the embryo and its supporting tissues, eventually leading to abortion [1]. This article only on mifepristone drugs