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急性肾病(急性肾衰) 诱发急性肾病药物数量似乎是无限的。急性肾衰病例中20—50%可能由药物所引起。急性肾病可表现为:①急性肾小管坏死(直接肾小管毒性);②急性肾动脉炎;③急性肾小球肾炎;④急性间质性肾炎;⑤急性肾小管梗阻(急性肾内梗阻)。引起上述疾病的药物相应有青霉素、金制剂、氨基甙类(如庆大霉素、卡那霉素、新霉素),金属中有汞、铋、锑和铜;溶剂中有四氯化碳,四氯乙烯和脂肪族二元醇类以及其它药物如水杨酸钠、两性霉素B、煤酚及蛇毒和蕈毒素;②解痉药,青霉素,磺胺类,噻嗪,苯异
Acute nephropathy (acute renal failure) appears to limit the number of drugs that cause acute kidney disease. 20-50% of acute renal failure cases may be caused by drugs. Acute nephropathy can be manifested as: acute tubular necrosis (direct tubular toxicity); acute renal artery inflammation; acute glomerulonephritis; acute interstitial nephritis; acute tubular obstruction (acute renal obstruction). The drugs that cause these diseases are penicillin, gold preparations, aminoglycosides (such as gentamicin, kanamycin, neomycin), mercury, bismuth, antimony and copper in the metal; carbon tetrachloride , Tetrachlorethylene and aliphatic diols and other drugs such as sodium salicylate, amphotericin B, coal phenol and snake venoms and muscarinic; ② antispasmodic drugs, penicillins, sulfonamides, thiazine, benzene