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目的:探讨婴儿唇裂气管插管全麻诱导的有效方法。方法:将80例先天性唇裂婴儿按手术时期先后分为γ-OH丁酸钠组,丙泊酚组。γ-OH丁酸钠组采用氯胺酮、γ-OH丁酸钠、地卡因,行静脉慢诱导气管插管全麻。丙泊酚组采用七氟烷、丙泊酚、瑞芬太尼、琥珀酰胆碱行静脉快诱导气管插管全麻。结果:两组麻醉诱导均平稳,肌松完善,喉头暴露充分,插管经过顺利,两组比较无统计学差异(P>0.05),仅γ-OH丁酸钠组出现1例轻度紫绀。结论:因γ-OH丁酸钠药物短缺,此方法不能应用于临床。七氟烷、丙泊酚、瑞芬太尼、琥珀酰胆碱行静脉快诱导气管插管全麻是目前最安全、最有效、最容易掌握的婴儿先天性唇裂气管插管全麻方法之一。
Objective: To investigate the effective method of induction of general anesthesia in the infant with cleft lip and tracheal intubation. Methods: Eighty cases of congenital cleft lip were divided into γ-OH sodium butyrate group and propofol group according to the operation period. γ-OH sodium butyrate group using ketamine, γ-OH sodium butyrate, tetracaine, intravenous slow intravenous intubation general anesthesia. Propofol group sevoflurane, propofol, remifentanil, succinylcholine intravenous induction of rapid tracheal intubation general anesthesia. Results: The induction of anesthesia in both groups was smooth, the muscle was perfect, the throat was well exposed and the intubation passed smoothly. There was no significant difference between the two groups (P> 0.05). Only 1 case of mild cyanosis occurred in the group of γ-OH sodium butyrate. Conclusion: This method can not be used clinically due to shortage of γ-OH sodium butyrate drug. Sevoflurane, propofol, remifentanil, succinylcholine intravenous catheterization tracheal intubation is the safest, most effective and easiest to grasp one of the congenital labial lip tracheal intubation general anesthesia .