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目的探究阿司匹林抵抗与缺血性脑血管病发生及复发之间的关系。方法选取南阳医专一附院神经内科2014年8月-2015年12月收治的220例缺血性脑血管疾病患者作为研究对象,根据患者血栓弹力图实验结果,将研究对象分为阿司匹林抵抗组(观察组,56例)和阿司匹林有效组(对照组,164例)。结果在缺血性脑血管病复发、周围血管栓塞、缺血性心血管病等方面,观察组发生率明显高于对照组,差异有统计学意义(P<0.01),而在其他原因死亡的发生率方面两组差异无统计学意义(P>0.05)。结论缺血性脑血管疾病的发生可能与阿司匹林抵抗有一定的关系。
Objective To investigate the relationship between aspirin resistance and the occurrence and recurrence of ischemic cerebrovascular disease. Methods A total of 220 patients with ischemic cerebrovascular diseases admitted from August 2014 to December 2015 in Nanyang Medical First Affiliated Hospital were enrolled. According to the results of thromboelastography test, the subjects were divided into aspirin resistance group (Observation group, 56 cases) and aspirin effective group (control group, 164 cases). Results The incidence of ischemic cerebrovascular disease, peripheral vascular embolism, ischemic cardiovascular disease and so on, the incidence of observation group was significantly higher than the control group, the difference was statistically significant (P <0.01), while in other causes of death The incidence of differences between the two groups was not statistically significant (P> 0.05). Conclusion The occurrence of ischemic cerebrovascular disease may be related to the resistance of aspirin.