偏头痛预防疗法目的是减少发作频率和减轻发作程度,最终改善偏头痛患者的生活质量。该疗法主要用于发作频率较高的患者,但患者是否愿意进行预防治疗与急性期治疗的有效性紧密关联。目前,日本预防疗法主要是普奈洛尔、阿米替林、丙戊酸和洛美利嗪,而血管紧张素Ⅱ受体阻断剂和肉毒素(BTX)有望成为新的偏头痛预防药物。 The objective of migraine prevention therapy is to reduce the frequency and severity of attacks and ultimately improve the quality of life in migraine sufferers. This therapy is mainly used in patients with high frequency of seizures, but whether patients are willing to carry out preventive treatment and the effectiveness of acute treatment are closely related. Prophylaxis in Japan is currently prednisolone, amitriptyline, valproic acid and lomerizine, and angiotensin II receptor blockers and botoxins (BTX) are expected to become the new migraine prophylaxis .